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see World Health Organization, Status of tobacco production and trade in Africa, 2021, Eric Crosbie et al., Tobacco supply and demand strategies used in African countries, Bulletin of the World Health Organization , 99, 7 (2021), 539540
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Overall, these results indicate that greater cumulative smoking exposure significantly increases both the risk and severity of liver fibrosis in MASLD
Superoxide in cigarette smoke is transported through the bloodstream to the vascular endothelium, where it reacts with nitric oxide to form peroxynitrite anion (ONOO), which is severely cytotoxic ( 29 )